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ea0032p688 | Neuroendocrinology | ECE2013

The characterization of sleep–wake pattern and its association with melatonin, as a marker of the circadian function of the suprachiasmatic nucleus, in craniopharyngioma patients

Jakobsen Line Pickering , Jennum Poul , Gammeltoft Steen , Feldt-Rasmussen Ulla , Klose Marianne

Hypothesis: We hypothesised that damage to the hypothalamus by local tumour, surgical treatment, or irradiation might involve the suprachiasmatic nucleus and thereby melatonin secretion, leading to disturbed circadian function and clinical manifestations such as daytime sleepiness and fatigue in craniopharyngeoma patients.Objective: We aimed to assess the influence of craniopharyngiomas and their treatment on melatonin secretion, sleep pattern, sleep qua...

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Endocrine Abstracts

The characterization of sleep–wake pattern and its association with melatonin, as a marker of the circadian function of the suprachiasmatic nucleus, in craniopharyngioma patients

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